neuroinflammation mechanisms and management.pdf

N EUROINFLAMMATION

Mechanisms and Management

S ECOND E DITION

Edited by

P AUL L. W OOD

H UMANA P RESS

N EUROINFLAMMATION

Contemporary Neuroscience

Neuroinflammation: Mechanisms and Man-

agement, Second Edition, edited by Paul L.

Wood , 2003

Neurobiology of Aggression: Understanding

and Preventing Violence, edited by Mark

P. Mattson , 2003

Neural Stem Cells for Brain and Spinal Cord

Repair, edited by Tanja Zigova, Evan Y.

Snyder, and Paul R. Sanberg, 2003

Neurotransmitter Transporters: Structure,

Function, and Regulation, Second Edition,

edited by Maarten E. A. Reith, 2002

The Neuronal Environment: Brain Homeostasis

in Health and Disease, edited by Wolfgang

Walz, 2002

Pathogenesis of Neurodegenerative Disorders,

edited by Mark P. Mattson , 2001

Stem Cells and CNS Development, edited by

Mahendra S. Rao, 2001

Neurobiology of Spinal Cord Injury, edited by

Robert G. Kalb and Stephen M. Strittmatter,

2000

Cerebral Signal Transduction: From First to

Fourth Messengers, edited by Maarten E.

A. Reith, 2000

Central Nervous System Diseases: Innovative

Animal Models from Lab to Clinic, edited by

Dwaine F. Emerich, Reginald L. Dean III,

and Paul R. Sanberg, 2000

Mitochondrial Inhibitors and Neurodegenera-

tive Disorders, edited by Paul R. Sanberg,

Hitoo Nishino, and Cesario V. Borlongan,

2000

Cerebral Ischemia: Molecular and Cellular Patho-

physiology, edited by Wolfgang Walz, 1999

Cell Transplantation for Neurological Disor-

ders, edited by Thomas B. Freeman and

Håkan Widner, 1998

Gene Therapy for Neurological Disorders

and Brain Tumors, edited by E. Antonio

Chiocca and Xandra O. Breakefield, 1998

Highly Selective Neurotoxins: Basic and Clini-

cal Applications, edited by Richard M.

Kostrzewa, 1998

Neuroinflammation: Mechanisms and Man-

agement, edited by Paul L. Wood, 1998

Neuroprotective Signal Transduction, edited

by Mark P. Mattson, 1998

Clinical Pharmacology of Cerebral Ischemia,

edited by Gert J. Ter Horst and Jakob

Korf, 1997

Molecular Mechanisms of Dementia, edited by

Wilma Wasco and Rudolph E. Tanzi, 1997

Neurotransmitter Transporters: Structure, Func-

tion, and Regulation, edited by Maarten E. A.

Reith, 1997

Motor Activity and Movement Disorders:

Research Issues and Applications, edited by

Paul R. Sanberg, Klaus-Peter Ossenkopp,

and Martin Kavaliers, 1996

Neurotherapeutics: Emerging Strategies,

edited by Linda M. Pullan and Jitendra

Patel, 1996

Neuron–Glia Interrelations During Phylog-

eny: II. Plasticity and Regeneration, edited

by Antonia Vernadakis and Betty I.

Roots, 1995

The Biology of Neuropeptide Y and Related

Peptides, edited by William F. Colmers

and Claes Wahlestedt, 1993

N EUROINFLAMMATION

Mechanisms and Management

S ECOND E DITION

Edited by

P AUL L. W OOD

Oxon Medica

South San Francisco, CA

H UMANA P RESS

T OTOWA , N EW J ERSEY

999 Riverview Drive, Suite 208

Totowa, New Jersey 07512

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Cover Illustration: Figure 4 from Chapter 16, “The Neuroinflammatory Components of the Trimethyltin (TMT) Model

of Hippocampal Neurodegeneration,” by G. Jean Harry and Christian Lefebvre d’Hellencourt.

Production Editor: Jessica Jannicelli.

Cover design by Patricia F. Cleary.

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Library of Congress Cataloging-in-Publication Data

Neuroinflammation : mechanisms and management / edited by Paul L. Wood.-- 2nd ed.

p. ; cm. -- (Contemporary neuroscience)

Includes bibliographical references and index.

ISBN 1-58829-002-6 (alk. paper) 1-59259-297-X (e-book)

1. Nervous system--Degeneration--Immunological aspects. 2. Inflammation. 3. Neuritis.

4. Inflammation--Mediators. 5. Nervous system--Pathophysiology. I. Wood, Paul L. II.

Series.

[DNLM: 1. Neurodegenerative Diseases--immunology. 2. Anti-Inflammatory

Agents--pharmacology. 3. Inflammation--immunology. 4. Nerve

Degeneration--immunology. 5. Neurodegenerative Diseases--drug therapy. WL 359

N49483 2003]

RC363 .N48 2003

616.8’0479--dc21

2002038760

This publication is printed on acid-free paper.

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