Autism Spectrum Disorders - The Role of Genetics in Diagnosis, Trtmt - S. Deutsch, et al., (Intech, 2011) WW.pdf

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AUTISM SPECTRUM
DISORDERS: THE ROLE OF
GENETICS IN DIAGNOSIS
AND TREATMENT
Edited by Stephen I. Deutsch
and Maria R. Urbano
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Autism Spectrum Disorders: The Role of Genetics in Diagnosis and Treatment
Edited by Stephen I. Deutsch and Maria R. Urbano
Published by InTech
Janeza Trdine 9, 51000 Rijeka, Croatia
Copyright © 2011 InTech
All chapters are Open Access articles distributed under the Creative Commons
Non Commercial Share Alike Attribution 3.0 license, which permits to copy,
distribute, transmit, and adapt the work in any medium, so long as the original
work is properly cited. After this work has been published by InTech, authors
have the right to republish it, in whole or part, in any publication of which they
are the author, and to make other personal use of the work. Any republication,
referencing or personal use of the work must explicitly identify the original source.
Statements and opinions expressed in the chapters are these of the individual contributors
and not necessarily those of the editors or publisher. No responsibility is accepted
for the accuracy of information contained in the published articles. The publisher
assumes no responsibility for any damage or injury to persons or property arising out
of the use of any materials, instructions, methods or ideas contained in the book.
Publishing Process Manager Ivana Lorkovic
Technical Editor Teodora Smiljanic
Cover Designer Jan Hyrat
Image Copyright A pyro Design, 2010. Used under license from Shutterstock.com
First published July, 2011
Printed in Croatia
A free online edition of this book is available at www.intechopen.com
Additional hard copies can be obtained from orders@intechweb.org
Autism Spectrum Disorders: The Role of Genetics in Diagnosis and Treatment, Edited by
Stephen I. Deutsch and Maria R. Urbano
p. cm.
ISBN 978-953-307-495-5
free online editions of InTech
Books and Journals can be found at
www.intechopen.com
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Contents
Preface IX
Part 1
Early Recognition and Diagnosis
1
Chapter 1
Early Detection of Autism Spectrum Disorders
3
Jariya Chuthapisith and Nichara Ruangdaraganon
Part 2
Nosology and Diagnostic Criteria:
What Makes Sense and Can Genetics Help?
15
Chapter 2
Pervasive Developmental Disorder- not
Otherwise Specified: Specifying and Differentiating
17
Koray Karabekiroglu
Chapter 3
Autism and Genetic Syndromes 31
Willem Verhoeven, Jos Egger and Ilse Feenstra
Part 3
Genetics and Pathophysiology
of Autism Spectrum Disorders
49
Chapter 4
The Genetics of Autism Spectrum Disorders
51
John J.M. Connolly and Hakon Hakonarson
Chapter 5
Genetic Heterogeneity of Autism Spectrum Disorders
65
Catherine Croft Swanwick,
Eric C. Larsen and Sharmila Banerjee-Basu
Chapter 6
The Genetic Basis of Phenotypic
Diversity: Autism as an Extreme
Tail of a Complex Dimensional Trait
83
Shinji Ijichi, Naomi Ijichi, Yukina Ijichi,
Hisami Sameshima and Hirofumi Morioka
Chapter 7
A New Genetic Mechanism for Autism
103
Julie Gauthier and Guy A. Rouleau
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