Bromocriptine-McDonald.pdf

Bromocriptine:

An Old Drug with New Uses

Lyle McDonald

This book is not intended for the treatment or prevention of disease, nor as a

substitute for medical treatment, nor as an alternative to medical advice. It is a review

of scientific evidence presented for information purposes only. Recommendations

outlined herein should not be adopted without a full review of the scientific references

provided and consultation with a physician. Use of the guidelines in this booklet is at

the sole choice and risk of the reader.

This book or any part thereof, may not be reproduced or recorded in any form without

permission in writing from the publisher, except for brief quotations embodied in

critical articles or reviews.

For information contact:

Lyle McDonald

500 E. Anderson Ln. #121-A

Austin, TX 78752

email: lylemcd@onr.com

ISBN: 0-9671456-1-9

FIRST EDITION

FIRST PRINTING

Acknowledgements

Generally, I want to thank all of the people who seem to enjoy what I have to

say, who read my articles, and who tell me that my advice has brought them results. I

wouldn’t keep doing this if they didn’t, and I wouldn’t be where I am today without these

folks’ support.

Specifically I want to thank all of my test readers and editors: Seth Breidbart,

Nina Bargiel, and Lester Long. Their comments, corrections, and endless feedback

prevented this from being another hard-to-read, typo-laden effort.

I want to give a special thanks to Shelly Hominuk, webmistress of

http://www.QFAC.com. First and foremost I want to thank her for her help in bringing

this book into existence, first in its digital form. She’s a techmistress in addition to

being a stone hottie. Also, I want to thank her for putting up with my shit for so many

years.

I also want to give a special thank you to Laura Moore, sex guru, for her

feedback on the small section about bromocriptine and sexual function. And for also

being a stone hottie who has put up with my shit for many years.

I want to give extra special thanks to my partner in crime: bench press stud and

endocrinology nerdette, Elzi Volk. On top of her editing efforts on this and my last

project, she has been a sounding board and constant source of questions, criticism,

and information over the years. She’s put up with more shit from me over the years

than I can ever thank her for. I am truly indebted to her.

It should go without saying but I’ll say it anyhow, Dan Duchaine (R.I.P.)

deserves a level of thanks I can never give him. He quite literally made me whatever I

am today. We miss you, Dan.

Finally, I want to give a super-duper extra-special thanks to John M. Williams.

Without his constant efforts , this project would never have become what it is.

Foreword

I’m assuming that most of you who have picked up this booklet know me

through my articles on the internet, the occasional print magazine work I’ve done, or

through my first book on ketogenic diets. If not, you have no clue to who I am so you

might as well just turn to Chapter 1. If you do know me, you probably know that I

usually don’t talk much about drugs. Contrary to what some have occasionally

suggested, this has nothing to do with any moral stance on my part.

Overall, I consider myself a libertarian when it comes to the use of drugs. As

long as the choice is made based on knowledge, and no one but the individual

making that choice is affected, what people do to themselves is their own business

as far as I’m concerned. So if it’s not some silly moral anti-drug stance, why don’t I

talk about drugs very much? There are a few reasons.

The main reason is that drug solutions for body recomposition (a fancy word

that means more muscle, less fat, or both) have never been my real interest or fort .

I’ve always been interested in pursuing better approaches to training or nutrition in

hopes that solutions would be forthcoming. Additionally, there were always people

out there who had forgotten more about drugs that I could ever know. I figured I’d leave

the drug stuff to them, and focus on my own area of expertise. Why try to compete with

guys who did nothing but research drug solutions when it wasn’t my major interest?

At the same time, I’ve always sort of kept myself aware of some of the drugs

that were floating around and looked into them from time to time. Sometimes finding

the way that certain drugs work can often lead to a more ’natural’ (a loaded word if ever

there were one) way of accomplishing the same thing. That is, figure out the

mechanism behind something like clenbuterol, and you can figure out ways to mimic

it to at least some degree with other compounds such as ephedrine.

As I’ve lost some of my youthful idealism, become more of a realist, and

learned more about human physiology, I’ve come to the rather depressing realization

that there are limits to what can be achieved ’naturally’. Our bodies are simply too

smart and too adaptable, which explains why most of what we do (or can do) only

works to a limited degree.

As I’ll detail in an upcoming book project (my magnum opus as it were), our

bodies are smarter than we are which is why most non-drug solutions are only

minimally effective. In a very real sense, in terms of what we typically want to

accomplish, our bodies hate us. Ten million plus years of evolution have made it so:

our bodies want to keep us alive and will do just about anything they can to do so.

Being lean or muscular beyond a certain point is generally not consistent with that

goal. Our bodies actively work to prevent it.

So I’ve become slightly more receptive to the idea of using drugs when there is

simply no other way to solve the problem. This assumes that they are safe, effective,

and affordable. Being legal, or at least in that gray area between legal and controlled

is important too. Going to jail to lose a few pounds of fat or gain a few pounds of

muscle is silly. So is throwing away your health or savings account, although people

do both all the time. So my criteria for a good drug are that it should be inexpensive,

available, effective, and safe (at least relatively speaking, there are risks with any

drugs).

Ephedrine is a good example of a drug that meets my criteria. Although it’s

becoming less readily available, it is inexpensive, effective, and has a solid decade of

research showing that it’s safe if used properly. Injectable growth hormone (GH) is an

example of a drug that doesn’t meet my criteria. It’s difficult to get, extremely

expensive, doesn’t really do that much, and has some problematic side effects.

This is a booklet about one of those drugs, a drug called bromocriptine, that

meets all of my criteria. It’s actually quite old and has been around for at least 3

decades. Bodybuilders used it in the 80’s for reasons other than what I’m going to

discuss in this book and I came across it while researching another topic. Looking

more deeply into its mechanisms of actions, I realized that it allowed us to solve one

of the more major body problems, which I’ll discuss soon enough.

With that out of the way, I don’t want anybody to think that I’m trying to become

some sort of ’drug guru’ with this booklet. It’s bad enough that people think of me as

the ’keto-guru’ after my first book since I happen to know about and advocate a lot of

different dietary approaches. Even then, people seem to think that all I like are

ketogenic diets, or that I think nothing else works.

In any event, I definitely don’t want anybody to be misled that I’m trying to

become the next big drug expert because of this booklet. Training and nutrition

physiology and how to manipulate them ’naturally’ are still my primary interests and I’ll

leave the bulk of the drug study to the other experts. This is simply a tangential project

on something I found very interesting. I hope you will too.

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